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Original Research Article Pages 4-9
Abstract: Researchers previously demonstrated that inclusion of iloprost, a pharmaceutical grade prostacyclin (PGI2), in culture media improves embryo development and pregnancy rates. Cultured embryos undergo apoptosis and studies have shown protection against apoptosis, rather than cell growth promotion, was the likely cause of iloprost's enhancing effect on embryos. Researchers have also established that embryos produce survivin, an antiapoptotic protein, which appears to be vital to normal development.
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